![]() ![]() Unintended consequences of long-term ADAM abuse include but are not limited to: Despite this, some common defects are observed within the larger Splicer population. The key is that the side effects were different with each individual. While some users broke out in horrible physical deformities, others like Sander Cohen suffered psychosis but few noticeable mutations. Due to the instability of its interaction with the subject, a whole host of deleterious reactions can manifest in the user. The very nature of the drug leads users into substance dependence.ĪDAM operates at the genetic level. In either case, ADAM, like other dangerous drugs, is addictive and prone to cause adverse side effects with extended use. However, it is possible there is no safe level of ADAM usage. The effects of small, controlled, or otherwise brief uses of Plasmids or Gene Tonics seem minimal. Brigid Tenenbaum, the genetic wonder drug works by exchanging original cells within a subject with new and changing variations. They are drug addicts, vicious animals.” ― Brigid Tenenbaum Īccording to ADAM's discoverer Dr. Īlthough the term Splicer can be applied to anyone who has altered their genetic structure with ADAM, it has since become the term used only to describe those who have become addicted to the substance, and had their minds and bodies ruined.Ġ9 October 2013 Symptoms “ Now, most who survive are like this: Splicers. Many still wear Masquerade Ball masks, perhaps, as Atlas suggests in BioShock, out of shame at how ADAM has deformed their bodies. They have become dependent on ADAM, both mentally and physically. Due to excessive ADAM consumption, their bodies and minds have been deformed beyond repair (though some of their physical deformities can be attributed to war scars or Dr. ![]() During the conflict, and the chaotic days that followed, most of the city's citizens fell victim to the Splicers or abused ADAM to the point of becoming Splicers themselves. Remnants of Rapture's human population, Splicers are the result of ADAM use, which skyrocketed during the violence of the Rapture Civil War. A man showing the early negative physical affects of splicing, preparing to throw a Hypnotize Plasmid.
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